Small Molecule

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API Technology Platform

BOC Sciences has established a state-of-the-art technology platform to support our API process research and manufacturing projects from laboratory scale to commercial scale. Aiming to achieve the goal of energy saving, consumption reduction, emission reduction and refinement and strengthening of API, our well-designed platform aims to provide novel green chemical pharmaceutical technology, process intensification technology, biocatalytic synthesis technology, microbial fermentation production technology, production equipment and optimization control technology and other key common technologies for API synthesis related to the huge market demand for the development of API industry.

API Technology PlatformFigure 1. API Technology: Resonant acoustic mixing technology. (Gerrard, S. E.; et al. 2019)

Our Services

To make it easier and better for researchers, BOC Sciences provides API Technology Platform service in a competitive fashion. We have provided a more efficient way to increase the number of new drugs, greatly shorten the R&D cycle, and reduce the development costs

Pharma crystallization

At BOC Sciences, our experts and scientific staffs have extensive expertise to provide effective solutions to CMC challenges associated with solid form and crystallization processes. Our teams are committed to investigating the underlying principles and mechanisms

High-potency APIs (HPAPIs) manufacturing

High-potency APIs represent an increasing proportion of the small molecule drug development process BOC Sciences offers an integrated HPAPI process development including analytical development, method validation, and multi-level production of high potency APIs and/or intermediates in a fully cGMP-compliant environment

Milling/Micronization of APIs

BOC Sciences has a highly skilled and dedicated, cross-functional team from the powder technology, analytical chemistry and production departments to ensure proper design and optimization of the milling/micronization process, full characterization and analysis of the milled product, and a fully cGMP compliant API milling/micronization environment

Continuous manufacturing technology

Our teams are committed to investing the development of R&D and production capabilities of flow chemistry continuously. We have abilities in improving the safety and efficiency of pharmaceutical production, diversifying the types of reactions that can be employed in the design of synthetic routes

Metal catalysis

Aiming to reduce sample amounts required for process and improve process efficiency, our advanced micro-metal screening platform is used to determine and optimize optimal conditions for Pd and Cu catalyzed coupling reactions such as Suzuki, Buchwald, Ullman and other types of C-C, C-N bond formation

Biocatalysis platform

Combined with our expert process chemistry and high-quality manufacturing assets, BOC Sciences has established a seamless and robust biocatalytic technology platform to screen, optimize and manufacture bio-catalysts for the production of relevant intermediates

Photocatalytic technology

We have established a photocatalytic technology R&D platform for photocatalytic reaction process screening and optimization, as well as the ability to perform kilogram-scale production. We are capable of performing wavelength screening and developing targeted photocatalytic reaction processes according to customer requirements

Hazard assessment

Developing safe, environmentally friendly and cost effective processes is the goal of our R&D team. When the use of hazardous chemicals cannot be avoided in a chemical process, BOC Sciences has professional expertise, rich experience and license to use or handle these hazardous chemicals

Why choose BOC Sciences?

Our dedicated CMC team has provided tailored solutions to our clients from engagement to launch. With many years of industry experience, we provide clients with the following:

  • Comprehensive, integrated CMC services with a flexible service model that grows with your programs
  • Knowledgeable industry experts who deliver scalable, actionable insights
  • World-class facilities and equipment that remain at the forefront of the global pharmaceutical research, analytical and development standards
  • Our comprehensive services support products at every stage of the product lifecycle, from early-stage discovery to full commercial cGMP manufacture
  • A focus on risk management that is designed to ensure completion of your technical goals

BOC Sciences provides professional, rapid and high-quality services of API technology platform at competitive prices for global customers. Personalized and customized services of API technology platform can satisfy any innovative scientific study demands. Our clients have direct access to our staff and prompt feedback to their inquiries. If you are interested in our services, please contact us immediately!


  1. Tanaka, R.; et al. Verification of the mixing processes of the active pharmaceutical ingredient, excipient and lubricant in a pharmaceutical formulation using a resonant acoustic mixing technology. RSC ADVANCES. 2016. 90.


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